October 16, 2025 • 8 min to read

Future-ready skin starts here. From daily rituals to advanced treatments, get ready to build skin longevity into your everyday.

Your complexion deserves more than a quick glow, it deserves lasting results and skin resilience. In this Q&A, Dr. Yannis explores how 111SKIN’s future-proof innovations, from 111CRYO and NMN masks, to exosome therapies and targeted supplements, come together to protect, repair and extend skin health for the long term. 

Skin longevity is the skin’s ability to maintain its optimal functions, repairing, protecting and renewing over the long term.

At 111SKIN, longevity is about more than immediate results; it’s about formulas and habits that go beyond the initial glow, preserving skin health so that radiance, firmness and resilience become your new baseline. 

Masks and treatments are effective for instant radiance and results, but high-performance, anti-ageing skincare and treatments extend those benefits over time, strengthening the skin’s resilience and supporting its natural repair processes —think of it as an investment in your skin’s long-term health.

For example, our Repair Serum NAC Y²™ goes beyond hydration for skin. Formulated with NAC Y²™, our proprietary complex inspired by post-surgical healing, it accelerates repair, fortifies the skin’s barrier and helps reduce sensitivity. Over time, this powerhouse formula builds skin that is tougher, less reactive, and more resistant to environmental stressors, ensuring that firmness, radiance, and vitality are sustained well beyond the glow. 

Rooted in medicine, 111SKIN combines advanced science with transformative rituals to support healthy skin and optimise how the skin behaves. NAC Y²™ was originally formulated with after I saw the effects of NAC on surgical healing. I enhanced these effects further by adding antioxidant Vitamin C and anti-inflammatory Escin to create NAC Y²™. Our proprietary compound boosts Glutathione to protect against stress and accelerate repair, while stimulating Vitamins E and C for collagen support and lasting radiance. 111SKIN’s longevity-led skincare and treatments amplify these benefits. For example -

• Exosome Face Lift stimulates cellular-signalling particles to encourage renewal.

• NMN Age-Defying Eye Masks target cell-renewal for optimum skin repair.

• Ultimate NAC Y2 ™ Complex boosts the skin’s ecosystem, offering nutrients from the inside out.

• 111CRYO improves microcirculation and promotes firm skin, collagen and elastin production. These benefits are also delivered by our Cryo Collection of masks and moisturisers.

Smart consistency is key. For your best skincare routine yet, approach it as a thoughtful daily practice, transforming each step into an intentional ritual that supports long-term vitality. Layering high-performance products, advanced treatments and targeted supplements ensures your routine works synergistically, nurturing skin from morning to night.

Here’s how to incorporate 111SKIN’s signature approach for youthful skin into your day:

Think of treatments as high-impact catalysts. 111CRYO, our whole-body cryotherapy system, supercharges skin health by boosting microcirculation and firmness, calming inflammation and stimulating collagen and elastin for long-term resilience. 

Our 111SKIN SPA/CLINIC partners, including our new Plaza Hotel New York, unite clinical precision, advanced technologies and indulgent wellness rituals for a truly transformative experience. Think exosome facials, cryo-infusions and targeted facials tailored to your skin’s longevity journey.

Your skin doesn’t exist in isolation; it’s fed and influenced by what goes inside. A well-designed supplement protocol, like Ultimate NAC Y2 ™ Complex provides essential cofactors for antioxidant systems, supports collagen synthesis and reduces systemic inflammation.

Formulated with NAC Y²™, Coenzyme Q10, Vitamins C, D, and E, plus Zinc, our Ultimate NAC Y2 ™ Complex supplement works to strengthen skin function, protect against oxidative stress and enhance natural rejuvenation.

Radiance and resilience are two sides of the same coin. Brightening masks refresh and illuminate the skin, creating an immediate, healthy glow that lifts and energises the complexion. Longevity-focused care works at a deeper, cellular level, supporting structure, collagen production, and ongoing skin vitality.

The NMN Age-Defying Eye Mask unites both approaches. It energises cells, stimulates collagen and enhances skin renewal, delivering luminous results you can see today, while strengthening the skin for tomorrow. It’s the perfect way to enjoy instant radiance alongside long-term wellness.

At 111SKIN, we don’t follow trends, we build from medical insight. Every formulation and treatment reflects over 30 years of experience in plastic and reconstructive surgery, from NAC Y²™ and exosome therapies to cryotherapy. We are proud to have opened the UK’s first electrically-powered whole-body cryotherapy suite, bringing cutting-edge science into a transformative experience. Through our global 111SKIN SPA/CLINIC network, we offer a complete longevity system, from daily skincare rituals at home to transformative, world-class treatments.

It’s never too late. Longevity works at every stage. Begin with the Repair Serum NAC Y2 ™ to strengthen and rebuild the skin’s barrier, then layer in Exosome Face Lift for targeted renewal. In-clinic therapies address deeper structural support, such as cryotherapy and collagen-infused facials.

Even in mature skin, targeted rituals and treatments can restore vitality while safeguarding against future signs of aging.

By combining mindful lifestyle habits with advanced treatments, you can enhance your longevity-led skincare routine, supporting repair, resilience and long-term vitality. Focus on choices that nurture both body and mind: