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NAC Y²™

111SKIN’s proprietary complex made up of Vitamin C, Escin and NAC designed to promote the production of glutathione, and encourage ongoing skin support, repair and rejuvenation while defending it from daily stressors.

The Origins of NAC Y²™:

A Surgeon’s Vision

When world-renowned surgeon Dr. Yannis Alexandrides set out to create a topical formula, his goal wasn’t to launch a skincare brand—it was to protect and prepare patients’ skin before and after surgery.

At the time, most products were too harsh for sensitized skin. Drawing on decades of clinical experience, Dr. Yannis turned to NAC (N-Acetyl Cysteine), a compound trusted in medicine and even studied for shielding astronauts from oxidative stress.

To boost its effects, he paired NAC with:

  • Vitamin C – Preserves NAC’s potency while brightening and defending skin.
  • Escin – Reduces inflammation and supports oxygen delivery.

Together, these ingredients form NAC Y²™, a pioneering complex that helps visibly repair, protect, and rejuvenate skin against daily stressors.

What NAC Y²™ Does for Your Skin

NAC Y²™ is more than just another anti-ageing ingredient—it’s a clinically tested complex designed to visibly repair, rejuvenate, and protect skin from daily stressors.

Improve elasticity and firmness

Visibly reduce fine lines and wrinkles

Protect against oxidative stress for long-term skin health

Reduce visible redness

The Product That Started It All:

The Repair Serum

Launched in 2012, the Repair Serum NAC Y²™ was the first 111SKIN product to introduce this pioneering complex, born as an evolution of the Healing Serum, originally created by Dr. Yannis for his clinical patients. The remarkable results seen in the clinic quickly led to wider demand, establishing Repair Serum NAC Y²™ as the brand’s first hero formula.

More than a decade later, it remains 111SKIN’s most iconic product.

Repair Serum NAC Y²™ CLINCAL RESULTS

92%

agree skin has a healthy glow**

92%

agree fine lines are visibly reduced**

2 Weeks

proven results for restoring healthy skin*

*Based on the results of a consumer trial on 100 participants after 6 weeks of twice daily product usage. **Based on the results of a consumer trial of 28 participants after 4 weeks.

DISCOVER POWERFUL NAC FORMULAS

Choose your free samples

You can pick up to 2 free samples.

Repair Serum NAC Y²™ 2ml

Repair Serum NAC Y²™ 2ml

Black Diamond Cream 2ml

Black Diamond Cream 2ml

Eye Lift Gel Y²™ 1ml

Eye Lift Gel Y²™ 1ml

Repair Day Cream 2ml

Repair Day Cream 2ml

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